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Desai SS, Tung JC, Zhou VX, Grenert JP, Malato Y, Rezvani M, Español-Suñer R, Willenbring H, Weaver VM, Chang TT
Physiological ranges of matrix rigidity modulate primary mouse hepatocyte function in part through hepatocyte nuclear factor 4 alpha.
Hepatology (Baltimore, Md.), 2016-03-09.
Mattis AN, Song G, Hitchner K, Kim RY, Lee AY, Sharma AD, Malato Y, McManus MT, Esau CC, Koller E, Koliwad S, Lim LP, Maher JJ, Raffai RL, Willenbring H
A screen in mice uncovers repression of lipoprotein lipase by microRNA-29a as a mechanism for lipid distribution away from the liver.
Hepatology (Baltimore, Md.), 2014-11-24.
Hentzschel F, Hammerschmidt-Kamper C, Börner K, Heiss K, Knapp B, Sattler JM, Kaderali L, Castoldi M, Bindman JG, Malato Y, Willenbring H, Mueller AK, Grimm D
AAV8-mediated in vivo overexpression of miR-155 enhances the protective capacity of genetically attenuated malarial parasites.
Molecular therapy : the journal of the American Society of Gene Therapy, 2014-09-05.
Johanna R. Schaub,Yann Malato,Coralie Gormond,Holger Willenbring
Evidence against a Stem Cell Origin of New Hepatocytes in a Common Mouse Model of Chronic Liver Injury.
Cell Reports, 2014-09-01.
Schaub JR, Malato Y, Gormond C, Willenbring H
Evidence against a stem cell origin of new hepatocytes in a common mouse model of chronic liver injury.
Cell reports, 2014-08-14.
Espejel S, Eckardt S, Harbell J, Roll GR, McLaughlin KJ, Willenbring H
Brief report: Parthenogenetic embryonic stem cells are an effective cell source for therapeutic liver repopulation.
Stem cells (Dayton, Ohio), 2014-07-01.
Lee RH, Roll G, Nguyen V, Willenbring H, Tang Q, Kang SM, Stock PG
Failure to achieve normal metabolic response in non-obese diabetic mice and streptozotocin-induced diabetic mice after transplantation of primary murine hepatocytes electroporated with the human proinsulin gene (p3MTChins).
Transplantation proceedings, 2014-07-01.
Ng R, Wu H, Xiao H, Chen X, Willenbring H, Steer CJ, Song G
Inhibition of microRNA-24 expression in liver prevents hepatic lipid accumulation and hyperlipidemia.
Hepatology (Baltimore, Md.), 2014-05-19.
Zhu S, Rezvani M, Harbell J, Mattis AN, Wolfe AR, Benet LZ, Willenbring H, Ding S
Mouse liver repopulation with hepatocytes generated from human fibroblasts.
Nature, 2014-02-23.
Mitchell C, Willenbring H
Addendum: A reproducible and well-tolerated method for 2/3 partial hepatectomy in mice.
Nature protocols, 2014-01-01.
Mathur A, Loskill P, Hong S, Lee J, Marcus SG, Dumont L, Conklin BR, Willenbring H, Lee LP, Healy KE
Human induced pluripotent stem cell-based microphysiological tissue models of myocardium and liver for drug development.
Stem cell research & therapy, 2013-12-20.
Lim L, Balakrishnan A, Huskey N, Jones KD, Jodari M, Ng R, Song G, Riordan J, Anderton B, Cheung ST, Willenbring H, Dupuy A, Chen X, Brown D, Chang AN, Goga A
MicroRNA-494 within an oncogenic microRNA megacluster regulates G1/S transition in liver tumorigenesis through suppression of mutated in colorectal cancer.
Hepatology (Baltimore, Md.), 2013-11-22.
Willenbring H, Soto-Gutierrez A
Transplantable liver organoids made from only three ingredients.
Cell stem cell, 2013-08-01.
Ma X, Duan Y, Tschudy-Seney B, Roll G, Behbahan IS, Ahuja TP, Tolstikov V, Wang C, McGee J, Khoobyari S, Nolta JA, Willenbring H, Zern MA
Highly efficient differentiation of functional hepatocytes from human induced pluripotent stem cells.
Stem cells translational medicine, 2013-05-16.
Willenbring H, Grompe M
A therapy for liver failure found in the JNK yard.
Cell, 2013-04-11.
M Evert,B Fan,Y Malato,S Ribback,F Dombrowski,H Willenbring,X Chen,DF Calvisi
Akt/Notch activation drives rapid cholangiocarcinoma development originating from mature hepatocytes in the mouse.
Zeitschrift für Gastroenterologie, 2013-01-11.
Fan B, Malato Y, Calvisi DF, Naqvi S, Razumilava N, Ribback S, Gores GJ, Dombrowski F, Evert M, Chen X, Willenbring H
Cholangiocarcinomas can originate from hepatocytes in mice.
The Journal of clinical investigation, 2012-07-17.
Mattis AN, Willenbring H
A ZFN/piggyBac step closer to autologous liver cell therapy.
Hepatology (Baltimore, Md.), 2012-06-01.
Ng R, Song G, Roll GR, Frandsen NM, Willenbring H
A microRNA-21 surge facilitates rapid cyclin D1 translation and cell cycle progression in mouse liver regeneration.
The Journal of clinical investigation, 2012-02-13.
Rountree CB, Mishra L, Willenbring H
Stem cells in liver diseases and cancer: recent advances on the path to new therapies.
Hepatology (Baltimore, Md.), 2012-01-01.
Malato Y, Naqvi S, Schürmann N, Ng R, Wang B, Zape J, Kay MA, Grimm D, Willenbring H
Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration.
The Journal of clinical investigation, 2011-11-21.
Willenbring H
A simple code for installing hepatocyte function.
Cell stem cell, 2011-08-05.
Eckardt S, McLaughlin KJ, Willenbring H
Mouse chimeras as a system to investigate development, cell and tissue function, disease mechanisms and organ regeneration.
Cell cycle (Georgetown, Tex.), 2011-07-01.
D'Alessio JA, Ng R, Willenbring H, Tjian R
Core promoter recognition complex changes accompany liver development.
Proceedings of the National Academy of Sciences of the United States of America, 2011-02-22.
Malato Y, Willenbring H
The MAP3K TAK1: a chock block to liver cancer formation.
Hepatology (Baltimore, Md.), 2010-10-01.
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