Publications

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Desai SS, Tung JC, Zhou VX, Grenert JP, Malato Y, Rezvani M, Español-Suñer R, Willenbring H, Weaver VM, Chang TT
Physiological ranges of matrix rigidity modulate primary mouse hepatocyte function in part through hepatocyte nuclear factor 4 alpha.
Hepatology (Baltimore, Md.), Jul-2016;64(1):261-75.  Epub 2016 Mar 9.
Rezvani M, Grimm AA, Willenbring H
Assessing the therapeutic potential of lab-made hepatocytes.
Hepatology (Baltimore, Md.), Jul-2016;64(1):287-94.  Epub 2016 May 26.
Rezvani M, Español-Suñer R, Malato Y, Dumont L, Grimm AA, Kienle E, Bindman JG, Wiedtke E, Hsu BY, Naqvi SJ, Schwabe RF, Corvera CU, Grimm D, Willenbring H
In  Vivo Hepatic Reprogramming of Myofibroblasts with AAV Vectors as a Therapeutic Strategy for Liver Fibrosis.
Cell stem cell, Jun-2-2016;18(6):809-16.
Hentzschel F, Hammerschmidt-Kamper C, Börner K, Heiss K, Knapp B, Sattler JM, Kaderali L, Castoldi M, Bindman JG, Malato Y, Willenbring H, Mueller AK, Grimm D
AAV8-mediated in vivo overexpression of miR-155 enhances the protective capacity of genetically attenuated malarial parasites.
Molecular therapy : the journal of the American Society of Gene Therapy, Dec-2014;22(12):2130-41.  Epub 2014 Sep 05.
Mattis AN, Song G, Hitchner K, Kim RY, Lee AY, Sharma AD, Malato Y, McManus MT, Esau CC, Koller E, Koliwad S, Lim LP, Maher JJ, Raffai RL, Willenbring H
A screen in mice uncovers repression of lipoprotein lipase by microRNA-29a as a mechanism for lipid distribution away from the liver.
Hepatology (Baltimore, Md.), Aug-18-2014;[Epub ahead of print].
Schaub JR, Malato Y, Gormond C, Willenbring H
Evidence against a Stem Cell Origin of New Hepatocytes in a Common Mouse Model of Chronic Liver Injury.
Cell reports, Aug-13-2014;[Epub ahead of print].
Ng R, Wu H, Xiao H, Chen X, Willenbring H, Steer CJ, Song G
Inhibition of microRNA-24 expression in liver prevents hepatic lipid accumulation and hyperlipidemia.
Hepatology (Baltimore, Md.), Aug-2014;60(2):554-64.  Epub 2014 May 19.
Espejel S, Eckardt S, Harbell J, Roll GR, McLaughlin KJ, Willenbring H
Brief report: Parthenogenetic embryonic stem cells are an effective cell source for therapeutic liver repopulation.
Stem cells (Dayton, Ohio), Jul-2014;32(7):1983-8.
Lee RH, Roll G, Nguyen V, Willenbring H, Tang Q, Kang SM, Stock PG
Failure to Achieve Normal Metabolic Response in Non-Obese Diabetic Mice and Streptozotocin-Induced Diabetic Mice After Transplantation of Primary Murine Hepatocytes Electroporated With the Human Proinsulin Gene (p3MTChins).
Transplantation proceedings, 2014 Jul-Aug;46(6):2002-6.
Mitchell C, Willenbring H
Addendum: A reproducible and well-tolerated method for 2/3 partial hepatectomy in mice.
Nature protocols, Jun-2014;9(6):.
Zhu S, Rezvani M, Harbell J, Mattis AN, Wolfe AR, Benet LZ, Willenbring H, Ding S
Mouse liver repopulation with hepatocytes generated from human fibroblasts.
Nature, Apr-3-2014;508(7494):93-7.  Epub 2014 Feb 23.
Lim L, Balakrishnan A, Huskey N, Jones KD, Jodari M, Ng R, Song G, Riordan J, Anderton B, Cheung ST, Willenbring H, Dupuy A, Chen X, Brown D, Chang AN, Goga A
MicroRNA-494 within an oncogenic microRNA megacluster regulates G1/S transition in liver tumorigenesis through suppression of mutated in colorectal cancer.
Hepatology (Baltimore, Md.), Jan-2014;59(1):202-15.  Epub 2013 Nov 22.
Ma X, Duan Y, Tschudy-Seney B, Roll G, Behbahan IS, Ahuja TP, Tolstikov V, Wang C, McGee J, Khoobyari S, Nolta JA, Willenbring H, Zern MA
Highly efficient differentiation of functional hepatocytes from human induced pluripotent stem cells.
Stem cells translational medicine, Jun-2013;2(6):409-19.  Epub 2013 May 16.
Mathur A, Loskill P, Hong S, Lee J, Marcus SG, Dumont L, Conklin BR, Willenbring H, Lee LP, Healy KE
Human induced pluripotent stem cell-based microphysiological tissue models of myocardium and liver for drug development.
Stem cell research & therapy, 2013;4 Suppl 1:S14.  Epub 2013 Dec 20.
Fan B, Malato Y, Calvisi DF, Naqvi S, Razumilava N, Ribback S, Gores GJ, Dombrowski F, Evert M, Chen X, Willenbring H
Cholangiocarcinomas can originate from hepatocytes in mice.
The Journal of clinical investigation, Aug-1-2012;122(8):2911-5.  Epub 2012 Jul 17.
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